The “lifeline” for all hemodialysis patients is the venous vascular access site, which must be cannulated three times per week during treatment. The “gold standard” for vascular access is the arteriovenous (AV) fistula, which has traditionally required open surgery to connect a patient’s native artery to a nearby vein. The AV fistula is preferred over synthetic grafts and central venous catheters because of its lower infection rate, prolonged survival, lower hospitalization rate and lower healthcare costs.1-3 And, patients with synthetic grafts or catheters have a 20% to 70% greater chance of death when compared to patients having an AV fistula.

The clinical references below detail the clinical studies, history and benefits of using an AV fistula for vascular access. Click on the icon or the title to view or download the PDF.

Hull JE, et al. Maturation for Hemodialysis in the Ellipsys Post-Market Registry. J Vasc Interv Radiol. In press August 2020.

Mallios A, et al. Endovascular Revision Using Distal Inflow: EndoRUDI. European Journal of Vascular and Endovascular Surgery, May 3, 2020.

Mallios A, et al. Percutaneous arteriovenous dialysis fistula. Journal of Vascular Surgery, January 6, 2020.

Franco G, et al. Feasibility for arteriovenous fistula creation with Ellipsys®. JVA, December 16, 2019.

Mallios A, Beathard GA, Litchfield T, Jennings WG. Early cannulation of percutaneously created arteriovenous hemodialysis fistulae. JVA. In Press Nov 2019.

Beathard GA, Litchfield T, Jennings WG. Two-year cumulative patency of endovascular arteriovenous fistula. JVA. In Press Sep 2019.

Aruny JE, Jennings WC, Lok, CE, Urbanes A. Percutaneous AV Creation in Practice. Endovascular Today.
Jun 2019 Vol 18, No 6.

Mullins D. Best Practices for Successful Cannulation of Percutaneous AVF. San Antonio Kidney Disease Access Center. Jun 2019.

Asif A, Bakr MM, Levitt M, Vachharajani T. Best Vascular Access in the Elderly: Time for Innovation? Blood Purif. Dec 5, 2018.

Mallios A, Jennings W. Early Cannulation of Percutaneously Created Arteriovenous Hemodialysis Fistulae. Poster Presentation at the 2018 meeting of the Vascular Access Society of the Americas, New Orleans, LA.

Mallios A, et al. Early results of percutaneous arteriovenous fistula creation with the Ellipsys Vascular Access System. Journal of Vascular Surgery. Oct 2018 Vol 68, No 4.

Jennings WC, Mallios A, Mushtaq N. Proximal radial artery arteriovenous fistula for hemodialysis vascular access. Journal of Vascular Surgery. Jan 2018 Vol 67 No 1.

Altman S, Peden EK, Turco M, McGuckin JF. Where Do You See Percutaneous Arteriovenous Fistula Creation Fitting Into Practices in the Next Several Years? Endovascular Today. Jun 2017 Vol 16, No 6.

Rajan DK, Hull JE, Clement J, Sidhu R, Thompson KR (Panel). The SIR 2016 Panel on Endovascular Arteriovenous Fistula Creation. Endovascular Today. June 2016 Vol 15 No 6.

Hull JE, Heath J, Bishop W. Supraclavicular Brachial Plexus Block for Arteriovenous Hemodialysis Access Procedures. JVIR. May 2016 Vol 27 No 5.

Hull JE, et al. Computational fluid dynamic evaluation of the side-to-side anastomosis for arteriovenous fistula. Journal of Vascular Surgery. Jul 2013 Vol 58 No 1.

2. Fistula First Breakthrough Initiative: Targeting Catheter Last in Fistula First, Vassalotti et al. Seminars in Dialysis – 2012.
3. A Practitioner’s Resource Guide to Hemodialysis Arteriovenous Fistulas, Fistula First, ESRD Network #14, 2003.

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